Month: November 2024

In collaboration with Prof. Yang Qu (UNB), we identify and characterize three new cytochrome P450 (CYP) enzymes that facilitate regio- and stereospecific oxidation of four monoterpene alkaloid (MIA) skeletons: iboga, aspidosperma, pseudoaspidosperma, and quebrachamine. From […]

We unveil and characterize a new N-methyltransferase (NMT) enzyme from the plant T. elegans: perivine Nβ-methyltransferase (TePeNMT). Enzyme kinetic experiments and enzyme homology modeling studies reveal the significant differences in enzyme active sites between TePeNMT […]